Cargando…
Dual TCR-Expressing T Cells in Cancer: How Single-Cell Technologies Enable New Investigation
TCR diversity measures are often used to understand the immune response in cancer. Traditional measures of diversity rely on bulk RNA sequencing (RNAseq) of the β-chain variable regions. However, the full αβ TCR repertoire is a combination of both the α- and β-chains, which are encoded by separate g...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AAI
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354877/ https://www.ncbi.nlm.nih.gov/pubmed/37129560 http://dx.doi.org/10.4049/immunohorizons.2200062 |