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Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway

BACKGROUND: Abnormal activation of microglia is involved in the pathogenesis of schizophrenia. Minocycline and antipsychotics have been reported to be effective in inhibiting the activation of microglia and thus alleviating the negative symptoms of patients with schizophrenia. However, the specific...

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Detalles Bibliográficos
Autores principales: Long, Yujun, Wang, Ying, Shen, Yidong, Huang, Jing, Li, Yamin, Wu, Renrong, Zhao, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354898/
https://www.ncbi.nlm.nih.gov/pubmed/37464316
http://dx.doi.org/10.1186/s12888-023-05014-1