Cargando…

Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway

BACKGROUND: Abnormal activation of microglia is involved in the pathogenesis of schizophrenia. Minocycline and antipsychotics have been reported to be effective in inhibiting the activation of microglia and thus alleviating the negative symptoms of patients with schizophrenia. However, the specific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Long, Yujun, Wang, Ying, Shen, Yidong, Huang, Jing, Li, Yamin, Wu, Renrong, Zhao, Jingping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354898/ https://www.ncbi.nlm.nih.gov/pubmed/37464316 http://dx.doi.org/10.1186/s12888-023-05014-1

Ejemplares similares

Benfotiamine Attenuates Inflammatory Response in LPS Stimulated BV-2 Microglia
por: Bozic, Iva, et al.
Publicado: (2015)

Naringin Regulates Microglia BV-2 Activation and Inflammation via the JAK/STAT3 Pathway
por: Li, Li, et al.
Publicado: (2022)

Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats
por: Zhu, Furong, et al.
Publicado: (2014)

Taraxasterol Inhibits LPS-Induced Inflammatory Response in BV2 Microglia Cells by Activating LXRα
por: Liu, Bin, et al.
Publicado: (2018)

Previous exposure to antipsychotic drug treatment is an effective predictor of metabolic disturbances experienced with current antipsychotic drug treatments
por: Yang, Ye, et al.
Publicado: (2022)

Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells
por: Standoli, Sara, et al.
Publicado: (2023)

Blueberry Counteracts BV-2 Microglia Morphological and Functional Switch after LPS Challenge
por: De Caris, Maria Giovanna, et al.
Publicado: (2020)

Response Profiles of BV2 Microglia to IFN-γ and LPS Co-Stimulation and Priming
por: Pan, Meng Liy, et al.
Publicado: (2023)

Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells
por: Porro, Chiara, et al.
Publicado: (2019)

Molecular Mechanisms of the Anti-Inflammatory Effects of Epigallocatechin 3-Gallate (EGCG) in LPS-Activated BV-2 Microglia Cells
por: Payne, Ashley, et al.
Publicado: (2023)

The effects of insulin on the inflammatory activity of BV2 microglia
por: Brabazon, Fiona, et al.
Publicado: (2018)

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
por: Li, Baojing, et al.
Publicado: (2022)

Atractylodis Rhizoma Alba Attenuates Neuroinflammation in BV2 Microglia upon LPS Stimulation by Inducing HO-1 Activity and Inhibiting NF-κB and MAPK
por: Jeong, Yun Hee, et al.
Publicado: (2019)

Angelicae Gigantis Radix Regulates LPS-Induced Neuroinflammation in BV2 Microglia by Inhibiting NF-κB and MAPK Activity and Inducing Nrf-2 Activity
por: Oh, You-Chang, et al.
Publicado: (2019)

Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia
por: Lo, Jung, et al.
Publicado: (2023)

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2017)

Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells
por: Zheng, Piao, et al.
Publicado: (2020)

TSPO Ligands Protect against Neuronal Damage Mediated by LPS-Induced BV-2 Microglia Activation
por: Ma, Baoyu, et al.
Publicado: (2022)

Caspase-1 inhibition attenuates activation of BV2 microglia induced by LPS-treated RAW264.7 macrophages
por: Pan, Yang, et al.
Publicado: (2016)

MAPK and JAK-STAT pathways dysregulation in plasmablastic lymphoma
por: Ramis-Zaldivar, Joan Enric, et al.
Publicado: (2021)

Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia
por: Das, Amitabh, et al.
Publicado: (2016)

Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS-induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF-κB signaling pathways
por: Yan, Aijuan, et al.
Publicado: (2017)

Intracellular Ca(2+) homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis
por: Lu, Yan, et al.
Publicado: (2017)

Anti-Inflammatory Effects of Progesterone in Lipopolysaccharide-Stimulated BV-2 Microglia
por: Lei, Beilei, et al.
Publicado: (2014)

Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia
por: Wang, Zhuo, et al.
Publicado: (2018)

Correction: 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ
por: Han, Qinghe, et al.
Publicado: (2018)

miRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia—Effect of cannabinoids
por: Juknat, Ana, et al.
Publicado: (2019)

Dexmedetomidine Attenuates Neuroinflammation In LPS-Stimulated BV2 Microglia Cells Through Upregulation Of miR-340
por: Bao, Yang, et al.
Publicado: (2019)

Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor
por: Jia, Yue, et al.
Publicado: (2021)

Aspirin-triggered lipoxin A(4 )attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells
por: Wang, Yan-Ping, et al.
Publicado: (2011)

Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
por: Oh, You-Chang, et al.
Publicado: (2021)

The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia
por: Fleiss, Bobbi, et al.
Publicado: (2015)

Characterization of Inflammatory Signals in BV-2 Microglia in Response to Wnt3a
por: Li, Cheng, et al.
Publicado: (2023)

Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
por: Scholz, Rebecca, et al.
Publicado: (2015)

Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells
por: Lee, Kang-Woo, et al.
Publicado: (2012)

Three Polymethoxyflavones Purified from Ougan (Citrus reticulata Cv. Suavissima) Inhibited LPS-Induced NO Elevation in the Neuroglia BV-2 Cell Line via the JAK2/STAT3 Pathway
por: Wang, Yue, et al.
Publicado: (2019)

Anti-neuroinflammatory Activity of Elephantopus scaber L. via Activation of Nrf2/HO-1 Signaling and Inhibition of p38 MAPK Pathway in LPS-Induced Microglia BV-2 Cells
por: Chan, Chim-Kei, et al.
Publicado: (2017)

Minocycline selectively inhibits M1 polarization of microglia
por: Kobayashi, K, et al.
Publicado: (2013)

Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models
por: Ganesan, Palanivel, et al.
Publicado: (2019)

Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia
por: Yuan, Yun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fh621at5m48aaijsn291gmq7p3