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Identification of cell subpopulations associated with disease phenotypes from scRNA-seq data using PACSI

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) has revolutionized the transcriptomics field by advancing analyses from tissue-level to cell-level resolution. Despite the great advances in the development of computational methods for various steps of scRNA-seq analyses, one major bottleneck of th...

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Detalles Bibliográficos
Autores principales: Liu, Chonghui, Zhang, Yan, Gao, Xin, Wang, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354926/
https://www.ncbi.nlm.nih.gov/pubmed/37468850
http://dx.doi.org/10.1186/s12915-023-01658-3