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Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription

BACKGROUND: How transcription factors (TFs) down-regulate gene expression remains ill-understood, especially when they bind to multiple enhancers contacting the same gene promoter. In particular, it is not known whether they exert similar or significantly different molecular effects at these enhance...

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Detalles Bibliográficos
Autores principales: Bejjani, Fabienne, Evanno, Emilie, Mahfoud, Samantha, Tolza, Claire, Zibara, Kazem, Piechaczyk, Marc, Jariel-Encontre, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354941/
https://www.ncbi.nlm.nih.gov/pubmed/37464380
http://dx.doi.org/10.1186/s13578-023-01077-5