PINNED: identifying characteristics of druggable human proteins using an interpretable neural network

The identification of human proteins that are amenable to pharmacologic modulation without significant off-target effects remains an important unsolved challenge. Computational methods have been devised to identify features which distinguish between “druggable” and “undruggable” proteins, finding th...

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Detalles Bibliográficos
Autores principales: Cunningham, Michael, Pins, Danielle, Dezső, Zoltán, Torrent, Maricel, Vasanthakumar, Aparna, Pandey, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354961/
https://www.ncbi.nlm.nih.gov/pubmed/37468968
http://dx.doi.org/10.1186/s13321-023-00735-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354961/
https://www.ncbi.nlm.nih.gov/pubmed/37468968
http://dx.doi.org/10.1186/s13321-023-00735-7

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