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Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time

BACKGROUND: Former critically ill children show an epigenetic age deceleration 2 years after paediatric intensive care unit (PICU) admission as compared with normally developing healthy children, with stunted growth in height 2 years further in time as physical correlate. This was particularly prono...

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Detalles Bibliográficos
Autores principales: Vanhorebeek, Ilse, Coppens, Grégoire, Güiza, Fabian, Derese, Inge, Wouters, Pieter J., Joosten, Koen F., Verbruggen, Sascha C., Van den Berghe, Greet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354984/
https://www.ncbi.nlm.nih.gov/pubmed/37468957
http://dx.doi.org/10.1186/s13148-023-01530-9