IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods

BACKGROUND: Integration site (IS) analysis is a fundamental analytical platform for evaluating the safety and efficacy of viral vector based preclinical and clinical Gene Therapy (GT). A handful of groups have developed standardized bioinformatics pipelines to process IS sequencing data, to generate...

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Detalles Bibliográficos
Autores principales: Yan, Aimin, Baricordi, Cristina, Nguyen, Quoc, Barbarossa, Luigi, Loperfido, Mariana, Biasco, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354991/
https://www.ncbi.nlm.nih.gov/pubmed/37464281
http://dx.doi.org/10.1186/s12859-023-05390-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354991/
https://www.ncbi.nlm.nih.gov/pubmed/37464281
http://dx.doi.org/10.1186/s12859-023-05390-1

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