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IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods
BACKGROUND: Integration site (IS) analysis is a fundamental analytical platform for evaluating the safety and efficacy of viral vector based preclinical and clinical Gene Therapy (GT). A handful of groups have developed standardized bioinformatics pipelines to process IS sequencing data, to generate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354991/ https://www.ncbi.nlm.nih.gov/pubmed/37464281 http://dx.doi.org/10.1186/s12859-023-05390-1 |