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Chronic intermittent hypoxia increases airway hyperresponsiveness during house dust mites exposures in rats

INTRODUCTION: Accumulating clinical evidence links Obstructive Sleep Apnea (OSA) with worse outcomes of asthma, but impact on airway function remains sparsely studied. We tested effects of Chronic Intermittent Hypoxia (CIH) – a hallmark of OSA – on airway hyperresponsiveness (AHR), in a rat model of...

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Detalles Bibliográficos
Autores principales: Teodorescu, Mihaela, Song, Ruolin, Brinkman, Jacqueline A., Sorkness, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355020/
https://www.ncbi.nlm.nih.gov/pubmed/37468919
http://dx.doi.org/10.1186/s12931-023-02493-4