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Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels

The present study was undertaken to explore the relative contributions of Cav3.2 T-type channels to mediating the antihyperalgesic activity of joint manipulation (JM) therapy. We used the chronic constriction injury model (CCI) to induce peripheral neuropathy and chronic pain in male mice, followed...

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Detalles Bibliográficos
Autores principales: Martins, Daniel F., Sorrentino, Victor, Mazzardo-Martins, Leidiane, Reed, William R., Santos, Adair R. S., Gadotti, Vinícius M., Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355051/
https://www.ncbi.nlm.nih.gov/pubmed/37464359
http://dx.doi.org/10.1186/s13041-023-01049-3