G3BP1-dependent mechanism suppressing protein aggregation in Huntington’s models and its demise upon stress granule assembly

Stress granules are membrane-less ribonucleoprotein organelles that assemble upon exposure to stress conditions, but rapidly disassemble upon removal of stress. However, chronic stress can lead to persistent stress granules, a feature of distinct age-related neurodegenerative disorders. Among them,...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Garcia, Ricardo, Koyuncu, Seda, Hommen, Franziska, Bilican, Saygın, Lee, Hyun Ju, Fatima, Azra, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355105/
https://www.ncbi.nlm.nih.gov/pubmed/36611004
http://dx.doi.org/10.1093/hmg/ddac304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355105/
https://www.ncbi.nlm.nih.gov/pubmed/36611004
http://dx.doi.org/10.1093/hmg/ddac304

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