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A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies

OBJECTIVE: A blood-based biomarker is needed to assess lupus nephritis (LN) disease activity, minimizing the need for invasive kidney biopsies. Long non-coding RNAs (lncRNAs) are known to regulate gene expression, appear to be stable in human plasma, and can serve as non-invasive biomarkers. METHODS...

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Detalles Bibliográficos
Autores principales: Sentis, George, Loukogiannaki, Catherine, Malissovas, Nikos, Nikolopoulos, Dionysis, Manolakou, Theodora, Flouda, Sofia, Grigoriou, Maria, Banos, Aggelos, Boumpas, Dimitrios T., Filia, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355154/
https://www.ncbi.nlm.nih.gov/pubmed/37475860
http://dx.doi.org/10.3389/fimmu.2023.1203848