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Extracellular matrix sensing via modulation of orientational order of integrins and F-actin in focal adhesions

Specificity of cellular responses to distinct cues from the ECM requires precise and sensitive decoding of physical information. However, how known mechanisms of mechanosensing like force-dependent catch bonds and conformational changes in FA proteins can confer that this sensitivity is not known. U...

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Detalles Bibliográficos
Autores principales: Grudtsyna, Valeriia, Packirisamy, Swathi, Bidone, Tamara C, Swaminathan, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355215/
https://www.ncbi.nlm.nih.gov/pubmed/37463754
http://dx.doi.org/10.26508/lsa.202301898