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Loss of polarity regulators initiates gasdermin-E-mediated pyroptosis in syncytiotrophoblasts

The syncytiotrophoblast is a human epithelial cell that is bathed in maternal blood on the maternal-facing surface of the human placenta. It therefore acts as a barrier and exchange interface between the mother and fetus. Syncytiotrophoblast dysfunction is a feature of pregnancy pathologies, like pr...

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Detalles Bibliográficos
Autores principales: Patel, Khushali, Nguyen, Jasmine, Shaha, Sumaiyah, Brightwell, Amy, Duan, Wendy, Zubkowski, Ashley, Domingo, Ivan K, Riddell, Meghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355286/
https://www.ncbi.nlm.nih.gov/pubmed/37468163
http://dx.doi.org/10.26508/lsa.202301946