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Regularized sequence-context mutational trees capture variation in mutation rates across the human genome
Germline mutation is the mechanism by which genetic variation in a population is created. Inferences derived from mutation rate models are fundamental to many population genetics methods. Previous models have demonstrated that nucleotides flanking polymorphic sites–the local sequence context–explain...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355397/ https://www.ncbi.nlm.nih.gov/pubmed/37418489 http://dx.doi.org/10.1371/journal.pgen.1010807 |