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Regularized sequence-context mutational trees capture variation in mutation rates across the human genome

Germline mutation is the mechanism by which genetic variation in a population is created. Inferences derived from mutation rate models are fundamental to many population genetics methods. Previous models have demonstrated that nucleotides flanking polymorphic sites–the local sequence context–explain...

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Detalles Bibliográficos
Autores principales: Adams, Christopher J., Conery, Mitchell, Auerbach, Benjamin J., Jensen, Shane T., Mathieson, Iain, Voight, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355397/
https://www.ncbi.nlm.nih.gov/pubmed/37418489
http://dx.doi.org/10.1371/journal.pgen.1010807

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