Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein

Computational methods were used to investigate six anthocyanidins exhibiting antidiabetic activity by inhibiting glucokinase regulatory protein (GKRP) activity. Density functional theory was used to optimise the geometry of anthocyanidins and calculate their quantum chemical properties. A blind dock...

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Detalles Bibliográficos
Autores principales: Kenneth, Christian, Anugrah, Daru Seto Bagus, Julianus, Jeffry, Junedi, Sendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355436/
https://www.ncbi.nlm.nih.gov/pubmed/37467274
http://dx.doi.org/10.1371/journal.pone.0288810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355436/
https://www.ncbi.nlm.nih.gov/pubmed/37467274
http://dx.doi.org/10.1371/journal.pone.0288810

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