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Molecular insights into the inhibitory potential of anthocyanidins on glucokinase regulatory protein
Computational methods were used to investigate six anthocyanidins exhibiting antidiabetic activity by inhibiting glucokinase regulatory protein (GKRP) activity. Density functional theory was used to optimise the geometry of anthocyanidins and calculate their quantum chemical properties. A blind dock...
Autores principales: | Kenneth, Christian, Anugrah, Daru Seto Bagus, Julianus, Jeffry, Junedi, Sendy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355436/ https://www.ncbi.nlm.nih.gov/pubmed/37467274 http://dx.doi.org/10.1371/journal.pone.0288810 |
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