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Lumicitabine, an orally administered nucleoside analog, in infants hospitalized with respiratory syncytial virus (RSV) infection: Safety, efficacy, and pharmacokinetic results

Respiratory syncytial virus (RSV) infection is the leading cause of infant hospitalizations and mortality. Lumicitabine, an oral nucleoside analog was studied for the treatment of RSV. The phase 1b and phase 2b studies reported here assessed the safety, pharmacokinetics, and pharmacodynamics of lumi...

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Detalles Bibliográficos
Autores principales: Oey, Abbie, McClure, Matthew, Symons, Julian A., Chanda, Sushmita, Fry, John, Smith, Patrick F., Luciani, Kathia, Fayon, Michael, Chokephaibulkit, Kulkanya, Uppala, Rattapon, Bernatoniene, Jolanta, Furuno, Kenji, Stanley, Thorsten, Huntjens, Dymphy, Witek, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355467/
https://www.ncbi.nlm.nih.gov/pubmed/37467213
http://dx.doi.org/10.1371/journal.pone.0288271