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Activation mechanism of a short argonaute-TIR prokaryotic immune system
Short prokaryotic argonaute (pAgo) and toll/interleukin-1 receptor/resistance protein (TIR)–analog of PAZ (APAZ) form a heterodimeric SPARTA complex that provides immunity to its prokaryotic host through an abortive infection mechanism. Monomeric SPARTA senses foreign RNA/DNA duplexes to assemble an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355822/ https://www.ncbi.nlm.nih.gov/pubmed/37467330 http://dx.doi.org/10.1126/sciadv.adh9002 |