Nonsteroidal anti-inflammatory drugs sensitize epithelial cells to Clostridioides difficile toxin–mediated mitochondrial damage

Clostridioides difficile damages the colonic mucosa through the action of two potent exotoxins. Factors shaping C. difficile pathogenesis are incompletely understood but are likely due to the ecological factors in the gastrointestinal ecosystem, mucosal immune responses, and environmental factors. L...

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Detalles Bibliográficos
Autores principales: Soto Ocaña, Joshua, Bayard, Nile U., Hart, Jessica L., Thomas, Audrey K., Furth, Emma E., Lacy, D. Borden, Aronoff, David M., Zackular, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355836/
https://www.ncbi.nlm.nih.gov/pubmed/37467340
http://dx.doi.org/10.1126/sciadv.adh5552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355836/
https://www.ncbi.nlm.nih.gov/pubmed/37467340
http://dx.doi.org/10.1126/sciadv.adh5552

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