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Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II

BACKGROUND: Prolonged activation of angiotensin II is the main mediator that contributes to the development of heart diseases, so converting angiotensin II into angiotensin 1‐7 has emerged as a new strategy to attenuate detrimental effects of angiotensin II. Prolylcarboxypeptidase is a lysosomal pro...

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Detalles Bibliográficos
Autores principales: Nguyen, Binh Y., Zhou, Fangchao, Binder, Pablo, Liu, Wei, Hille, Susanne S., Luo, Xiaojing, Zi, Min, Zhang, Hongyuan, Adamson, Antony, Ahmed, Fozia Z., Butterworth, Sam, Cartwright, Elizabeth J., Müller, Oliver J., Guan, Kaomei, Fitzgerald, Elizabeth M., Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356030/
https://www.ncbi.nlm.nih.gov/pubmed/37318028
http://dx.doi.org/10.1161/JAHA.122.028298