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Loss of PI3Kα Mediates Protection From Myocardial Ischemia–Reperfusion Injury Linked to Preserved Mitochondrial Function

BACKGROUND: Identifying new therapeutic targets for preventing the myocardial ischemia–reperfusion injury would have profound implications in cardiovascular medicine. Myocardial ischemia–reperfusion injury remains a major clinical burden in patients with coronary artery disease. METHODS AND RESULTS:...

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Detalles Bibliográficos
Autores principales: Zhabyeyev, Pavel, McLean, Brent, Bassiouni, Wesam, Valencia, Robert, Paul, Manish, Darwesh, Ahmed M., Seubert, John M., Hazra, Saugata, Oudit, Gavin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356046/
https://www.ncbi.nlm.nih.gov/pubmed/37318009
http://dx.doi.org/10.1161/JAHA.122.022352