DDX41-associated susceptibility to myeloid neoplasms

Deleterious germ line DDX41 variants confer risk for myeloid neoplasms (MNs) and less frequently for lymphoid malignancies, with autosomal dominant inheritance and an estimated prevalence of 3% among MNs. Germ line DDX41 variants include truncating alleles that comprise about two-thirds of all allel...

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Detalles Bibliográficos
Autores principales: Makishima, Hideki, Bowman, Teresa V., Godley, Lucy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Germ Line Predisposition to Hematologic Malignancies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356560/
https://www.ncbi.nlm.nih.gov/pubmed/36455200
http://dx.doi.org/10.1182/blood.2022017715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356560/
https://www.ncbi.nlm.nih.gov/pubmed/36455200
http://dx.doi.org/10.1182/blood.2022017715

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