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Cryo-EM structure of coagulation factor V short

Coagulation factor V (fV) is the precursor of activated fV (fVa), an essential component of the prothrombinase complex required for the rapid activation of prothrombin in the penultimate step of the coagulation cascade. In addition, fV regulates the tissue factor pathway inhibitor α (TFPIα) and prot...

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Detalles Bibliográficos
Autores principales: Mohammed, Bassem M., Pelc, Leslie A., Rau, Michael J., Di Cera, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356581/
https://www.ncbi.nlm.nih.gov/pubmed/36862974
http://dx.doi.org/10.1182/blood.2022019486