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Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution

Skeletal muscle fibers express distinct gene programs during development and maturation, but the underlying gene regulatory networks that confer stage-specific myofiber properties remain unknown. To decipher these distinctive gene programs and how they respond to neural activity, we generated a comb...

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Detalles Bibliográficos
Autores principales: Dos Santos, Matthieu, Shah, Akansha M., Zhang, Yichi, Bezprozvannaya, Svetlana, Chen, Kenian, Xu, Lin, Lin, Weichun, McAnally, John R., Bassel-Duby, Rhonda, Liu, Ning, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356771/
https://www.ncbi.nlm.nih.gov/pubmed/37468485
http://dx.doi.org/10.1038/s41467-023-40073-8