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The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice

Skeletal muscle and thermogenic adipose tissue are both critical for the maintenance of body temperature in mammals. However, whether these two tissues are interconnected to modulate thermogenesis and metabolic homeostasis in response to thermal stress remains inconclusive. Here, we report that huma...

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Detalles Bibliográficos
Autores principales: Jin, Lu, Han, Shuang, Lv, Xue, Li, Xiaofei, Zhang, Ziyin, Kuang, Henry, Chen, Zhimin, Lv, Cheng-an, Peng, Wei, Yang, Zhuoying, Yang, Miqi, Mi, Lin, Liu, Tongyu, Ma, Shengshan, Qiu, Xinyuan, Wang, Qintao, Pan, Xiaowen, Shan, Pengfei, Feng, Yu, Li, Jin, Wang, Fudi, Xie, Liwei, Zhao, Xuyun, Fu, Jun-Fen, Lin, Jiandie D., Meng, Zhuo-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356794/
https://www.ncbi.nlm.nih.gov/pubmed/37468484
http://dx.doi.org/10.1038/s41467-023-39710-z