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The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice
Skeletal muscle and thermogenic adipose tissue are both critical for the maintenance of body temperature in mammals. However, whether these two tissues are interconnected to modulate thermogenesis and metabolic homeostasis in response to thermal stress remains inconclusive. Here, we report that huma...
Autores principales: | Jin, Lu, Han, Shuang, Lv, Xue, Li, Xiaofei, Zhang, Ziyin, Kuang, Henry, Chen, Zhimin, Lv, Cheng-an, Peng, Wei, Yang, Zhuoying, Yang, Miqi, Mi, Lin, Liu, Tongyu, Ma, Shengshan, Qiu, Xinyuan, Wang, Qintao, Pan, Xiaowen, Shan, Pengfei, Feng, Yu, Li, Jin, Wang, Fudi, Xie, Liwei, Zhao, Xuyun, Fu, Jun-Fen, Lin, Jiandie D., Meng, Zhuo-Xian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356794/ https://www.ncbi.nlm.nih.gov/pubmed/37468484 http://dx.doi.org/10.1038/s41467-023-39710-z |
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