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3-Hydroxy coumarin demonstrates anti-biofilm and anti-hyphal efficacy against Candida albicans via inhibition of cell-adhesion, morphogenesis, and virulent genes regulation

Candida albicans, a common fungus of human flora, can become an opportunistic pathogen and causes invasive candidiasis in immunocompromised individuals. Biofilm formation is the prime cause of antibiotic resistance during C. albicans infections and treating biofilm-forming cells is challenging due t...

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Detalles Bibliográficos
Autores principales: Sushmitha, T. J., Rajeev, Meora, Kathirkaman, Vellaisamy, Shivam, Singh, Rao, Toleti Subba, Pandian, Shunmugiah Karutha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356798/
https://www.ncbi.nlm.nih.gov/pubmed/37468600
http://dx.doi.org/10.1038/s41598-023-37851-1