Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington’s disease

RNA-binding proteins (RBPs) are key players regulating RNA processing and are associated with disorders ranging from cancer to neurodegeneration. Here, we present a proteomics workflow for large-scale identification of RBPs and their RNA-binding regions in the mammalian brain identifying 526 RBPs. A...

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Detalles Bibliográficos
Autores principales: Mullari, Meeli, Fossat, Nicolas, Skotte, Niels H., Asenjo-Martinez, Andrea, Humphreys, David T., Bukh, Jens, Kirkeby, Agnete, Scheel, Troels K. H., Nielsen, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356804/
https://www.ncbi.nlm.nih.gov/pubmed/37468457
http://dx.doi.org/10.1038/s41467-023-39936-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356804/
https://www.ncbi.nlm.nih.gov/pubmed/37468457
http://dx.doi.org/10.1038/s41467-023-39936-x

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