Identifying and profiling structural similarities between Spike of SARS-CoV-2 and other viral or host proteins with Machaon

Using protein structure to predict function, interactions, and evolutionary history is still an open challenge, with existing approaches relying extensively on protein homology and families. Here, we present Machaon, a data-driven method combining orientation invariant metrics on phi-psi angles, int...

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Detalles Bibliográficos
Autores principales: Kakoulidis, Panos, Vlachos, Ioannis S., Thanos, Dimitris, Blatch, Gregory L., Emiris, Ioannis Z., Anastasiadou, Ema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356814/
https://www.ncbi.nlm.nih.gov/pubmed/37468602
http://dx.doi.org/10.1038/s42003-023-05076-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356814/
https://www.ncbi.nlm.nih.gov/pubmed/37468602
http://dx.doi.org/10.1038/s42003-023-05076-7

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