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Identifying and profiling structural similarities between Spike of SARS-CoV-2 and other viral or host proteins with Machaon
Using protein structure to predict function, interactions, and evolutionary history is still an open challenge, with existing approaches relying extensively on protein homology and families. Here, we present Machaon, a data-driven method combining orientation invariant metrics on phi-psi angles, int...
Autores principales: | Kakoulidis, Panos, Vlachos, Ioannis S., Thanos, Dimitris, Blatch, Gregory L., Emiris, Ioannis Z., Anastasiadou, Ema |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356814/ https://www.ncbi.nlm.nih.gov/pubmed/37468602 http://dx.doi.org/10.1038/s42003-023-05076-7 |
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