Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation

Inflammation leads to functional iron deficiency by increasing the expression of the hepatic iron regulatory peptide hepcidin. Inflammation also stimulates fibroblast growth factor 23 (FGF23) production by increasing both Fgf23 transcription and FGF23 cleavage, which paradoxically leads to excess in...

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Detalles Bibliográficos
Autores principales: Courbon, Guillaume, Thomas, Jane Joy, Martinez-Calle, Marta, Wang, Xueyan, Spindler, Jadeah, Von Drasek, John, Hunt-Tobey, Bridget, Mehta, Rupal, Isakova, Tamara, Chang, Wenhan, Creemers, John W. M., Ji, Peng, Martin, Aline, David, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356820/
https://www.ncbi.nlm.nih.gov/pubmed/37053547
http://dx.doi.org/10.1182/blood.2022018475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356820/
https://www.ncbi.nlm.nih.gov/pubmed/37053547
http://dx.doi.org/10.1182/blood.2022018475

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