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GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach
GPCRs are master regulators of cell signaling by transducing extracellular stimuli into the cell via selective coupling to intracellular G-proteins. Here we present a computational analysis of the structural determinants of G-protein-coupling repertoire of experimental and predicted 3D GPCR-G-protei...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356834/ https://www.ncbi.nlm.nih.gov/pubmed/37468476 http://dx.doi.org/10.1038/s41467-023-40045-y |