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GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach

GPCRs are master regulators of cell signaling by transducing extracellular stimuli into the cell via selective coupling to intracellular G-proteins. Here we present a computational analysis of the structural determinants of G-protein-coupling repertoire of experimental and predicted 3D GPCR-G-protei...

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Detalles Bibliográficos
Autores principales: Matic, Marin, Miglionico, Pasquale, Tatsumi, Manae, Inoue, Asuka, Raimondi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356834/
https://www.ncbi.nlm.nih.gov/pubmed/37468476
http://dx.doi.org/10.1038/s41467-023-40045-y