Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome data analysis

The polycystic ovarian syndrome (PCOS) is closely associated with enhanced apoptosis of granulosa cells, which have a vital role in maturation of oocytes. p53 plays a critical role in the regulation of apoptosis and cell cycle arrest, metabolism and insulin resistance. The aim of this study was to i...

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Detalles Bibliográficos
Autores principales: Zanjirband, M., Hodayi, R., Safaeinejad, Z., Nasr-Esfahani, M. H., Ghaedi-Heydari, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356838/
https://www.ncbi.nlm.nih.gov/pubmed/37468508
http://dx.doi.org/10.1038/s41598-023-38340-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356838/
https://www.ncbi.nlm.nih.gov/pubmed/37468508
http://dx.doi.org/10.1038/s41598-023-38340-1

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