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Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines

PURPOSE: A wide therapeutic repertoire has become available to oncologists including radio- and chemotherapy, small molecules and monoclonal antibodies. However, drug efficacy can be limited by genetic heterogeneity. Here, we designed a webtool that facilitates the data analysis of the in vitro drug...

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Detalles Bibliográficos
Autores principales: Boeschen, Myriam, Le Duc, Diana, Stiller, Mathias, von Laffert, Maximilian, Schöneberg, Torsten, Horn, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356876/
https://www.ncbi.nlm.nih.gov/pubmed/36472769
http://dx.doi.org/10.1007/s00432-022-04503-2