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TLR7/8 activation induces autoimmune vasculopathy and causes severe pulmonary arterial hypertension
This study introduced a combination of autoimmune stimuli (TLR-7/8 agonist) and endothelial injury (Sugen) and established a novel rat model representing immune–vascular pathological events mimicking human PAH associated with autoimmune disorders https://bit.ly/3P3H5V0
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356963/ https://www.ncbi.nlm.nih.gov/pubmed/37290790 http://dx.doi.org/10.1183/13993003.00204-2023 |