TLR7/8 activation induces autoimmune vasculopathy and causes severe pulmonary arterial hypertension

This study introduced a combination of autoimmune stimuli (TLR-7/8 agonist) and endothelial injury (Sugen) and established a novel rat model representing immune–vascular pathological events mimicking human PAH associated with autoimmune disorders https://bit.ly/3P3H5V0

Detalles Bibliográficos
Autores principales: Yeh, Fu-Chiang, Chen, Chien-Nien, Xie, Chong-Yang, Baxan, Nicoleta, Zhao, Lin, Ashek, Ali, Sabrin, Farah, Lawrie, Allan, Wilkins, Martin, Zhao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356963/
https://www.ncbi.nlm.nih.gov/pubmed/37290790
http://dx.doi.org/10.1183/13993003.00204-2023

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