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Retinoic acid is dispensable for meiotic initiation but required for spermiogenesis in the mammalian testis

Retinoic acid (RA) is the proposed mammalian ‘meiosis inducing substance’. However, evidence for this role comes from studies in the fetal ovary, where germ cell differentiation and meiotic initiation are temporally inseparable. In the postnatal testis, these events are separated by more than 1 week...

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Detalles Bibliográficos
Autores principales: Kirsanov, Oleksandr, Johnson, Taylor A., Niedenberger, Bryan A., Malachowski, Taylor N., Hale, Benjamin J., Chen, Qing, Lackford, Brad, Wang, Jiajia, Singh, Anukriti, Schindler, Karen, Hermann, Brian P., Hu, Guang, Geyer, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357014/
https://www.ncbi.nlm.nih.gov/pubmed/37350382
http://dx.doi.org/10.1242/dev.201638