Cargando…
Aggregation-prone Tau impairs mitochondrial import, which affects organelle morphology and neuronal complexity
Mitochondrial protein import is essential for organellar biogenesis, and thereby for the sufficient supply of cytosolic ATP – which is particularly important for cells with high energy demands like neurons. This study explores the prospect of import machinery perturbation as a cause of neurodegenera...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357015/ https://www.ncbi.nlm.nih.gov/pubmed/37303235 http://dx.doi.org/10.1242/jcs.260993 |