Extracellular Tau Oligomers Damage the Axon Initial Segment

BACKGROUND: In Alzheimer’s disease (AD) brain, neuronal polarity and synaptic connectivity are compromised. A key structure for regulating polarity and functions of neurons is the axon initial segment (AIS), which segregates somatodendritic from axonal proteins and initiates action potentials. Toxic...

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Detalles Bibliográficos
Autores principales: Best, Merci N., Lim, Yunu, Ferenc, Nina N., Kim, Nayoung, Min, Lia, Wang, Dora Bigler, Sharifi, Kamyar, Wasserman, Anna E., McTavish, Sloane A., Siller, Karsten H., Jones, Marieke K., Jenkins, Paul M., Mandell, James W., Bloom, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357156/
https://www.ncbi.nlm.nih.gov/pubmed/37182881
http://dx.doi.org/10.3233/JAD-221284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357156/
https://www.ncbi.nlm.nih.gov/pubmed/37182881
http://dx.doi.org/10.3233/JAD-221284

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