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Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies

BACKGROUND: Pathological tau proteins constitute neurofibrillary tangles that accumulate in tauopathies including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP), and familial frontotemporal lobar degeneration (FTLD-Tau). We previously showed that the FKBP52 immunophilin interacts fun...

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Detalles Bibliográficos
Autores principales: Meduri, Geri, Guillemeau, Kevin, Daguinot, Corentin, Dounane, Omar, Genet, Melanie, Ferrara, Luigi, Chambraud, Beatrice, Baulieu, Etienne Emile, Giustiniani, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357213/
https://www.ncbi.nlm.nih.gov/pubmed/37248902
http://dx.doi.org/10.3233/JAD-230127