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Prodromal Glutamatergic Modulation with Riluzole Impacts Glucose Homeostasis and Spatial Cognition in Alzheimer’s Disease Mice
BACKGROUND: Prior research supports a strong link between Alzheimer’s disease (AD) and metabolic dysfunction that involves a multi-directional interaction between glucose, glutamatergic homeostasis, and amyloid pathology. Elevated soluble amyloid-β (Aβ) is an early biomarker for AD-associated cognit...
Autores principales: | Findley, Caleigh A., McFadden, Samuel A., Cox, MaKayla F., Sime, Lindsey N., Peck, Mackenzie R., Quinn, Kathleen, Bartke, Andrzej, Hascup, Kevin N., Hascup, Erin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357216/ https://www.ncbi.nlm.nih.gov/pubmed/37248899 http://dx.doi.org/10.3233/JAD-221245 |
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