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Triple combination of lomustine, temozolomide and irradiation reduces canine glioma cell survival in vitro

BACKGROUND: Combined chemoradiation offers a promising therapeutic strategy for dogs with glioma. The alkylating agents temozolomide (TMZ) and lomustine (CCNU) penetrate the blood‐brain barrier, and doses for dogs are established. Whether such combinations are clinically advantageous remains to be e...

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Detalles Bibliográficos
Autores principales: Fuchs, Daniel, Rohrer Bley, Carla, Morandi, Luca, Tonon, Caterina, Weyland, Mathias S., Nytko, Katarzyna J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357258/
https://www.ncbi.nlm.nih.gov/pubmed/37365849
http://dx.doi.org/10.1002/vms3.1181