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Study protocol for investigating the clinical performance of an automated blood test for glial fibrillary acidic protein and ubiquitin carboxy-terminal hydrolase L1 blood concentrations in elderly patients with mild traumatic BRAIN Injury and reference values (BRAINI-2 Elderly European study): a prospective multicentre observational study

INTRODUCTION: Two blood brain-derived biomarkers, glial fibrillar acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), can rule out intracranial lesions in patients with mild traumatic brain injury (mTBI) when assessed within the first 12 hours. Most elderly patients were excl...

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Detalles Bibliográficos
Autores principales: Lagares, Alfonso, Payen, Jean-François, Biberthaler, Peter, Poca, M Antonia, Méjan, Odile, Pavlov, Vladislav, Viglino, Damien, Sapin, Vincent, Lassaletta, Aurora, de la Cruz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357305/
https://www.ncbi.nlm.nih.gov/pubmed/37460257
http://dx.doi.org/10.1136/bmjopen-2022-071467