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Study protocol for investigating the clinical performance of an automated blood test for glial fibrillary acidic protein and ubiquitin carboxy-terminal hydrolase L1 blood concentrations in elderly patients with mild traumatic BRAIN Injury and reference values (BRAINI-2 Elderly European study): a prospective multicentre observational study
INTRODUCTION: Two blood brain-derived biomarkers, glial fibrillar acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), can rule out intracranial lesions in patients with mild traumatic brain injury (mTBI) when assessed within the first 12 hours. Most elderly patients were excl...
Autores principales: | Lagares, Alfonso, Payen, Jean-François, Biberthaler, Peter, Poca, M Antonia, Méjan, Odile, Pavlov, Vladislav, Viglino, Damien, Sapin, Vincent, Lassaletta, Aurora, de la Cruz, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357305/ https://www.ncbi.nlm.nih.gov/pubmed/37460257 http://dx.doi.org/10.1136/bmjopen-2022-071467 |
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