Claustral neurons projecting to frontal cortex restrict opioid consumption

The synthetic opioid fentanyl is a major contributor to the current opioid addiction crisis. We report that claustral neurons projecting to the frontal cortex limit oral fentanyl self-administration in mice. We found that fentanyl transcriptionally activates frontal-projecting claustrum neurons. The...

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Detalles Bibliográficos
Autores principales: Terem, Anna, Fatal, Yonatan, Peretz-Rivlin, Noa, Turm, Hagit, Koren, Shahar Shohat, Kitsberg, Danny, Ashwal-Fluss, Reut, Mukherjee, Diptendu, Habib, Naomi, Citri, Ami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357322/
https://www.ncbi.nlm.nih.gov/pubmed/37379841
http://dx.doi.org/10.1016/j.cub.2023.05.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357322/
https://www.ncbi.nlm.nih.gov/pubmed/37379841
http://dx.doi.org/10.1016/j.cub.2023.05.065

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