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Identified Isosteric Replacements of Ligands’ Glycosyl Domain by Data Mining
[Image: see text] Biologically equivalent replacements of key moieties in molecules rationalize scaffold hopping, patent busting, or R-group enumeration. Yet, this information may depend upon the expert-defined space, and might be subjective and biased toward the chemistries they get used to. Most i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357434/ https://www.ncbi.nlm.nih.gov/pubmed/37483233 http://dx.doi.org/10.1021/acsomega.3c02243 |